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SexualBremelanotide®Vyleesi®

PT-141 dosing reference

Common vial sizes, typical dose ranges, and a free reconstitution calculator pre-configured for PT-141. Not medical advice. Always verify against your vial label and your provider's protocol.

Vial sizes
10 mg
Typical dose
1–2 mg
Absolute max
3 mg
BAC water
1, 2 ml

PT-141 reconstitution

Pre-loaded with common PT-141 values — adjust to your vial.

Inputs

Peptide preset
Syringe

PT-141 common vial sizes: 10 mg. Typical dose range: 12 mg. Clinical literature. Not medical advice.

Draw on U-100
10.0units

for a 1 mg dose

Concentration
10.0 mg/ml
Volume
0.100 ml
Per ml
100 u

Not medical advice. Always verify against your vial label and your provider's instructions. Re-check before drawing.

About PT-141

Sexual-function peptides include PT-141 (bremelanotide, a melanocortin agonist) and melanotan II (tanning + libido). They are studied for arousal and pigmentation.

  • How it's used

    Subcutaneous injection on-demand (PT-141) or in loading + maintenance cycles (melanotan II).

  • Storage

    Refrigerate reconstituted vials.

  • Watch for

    • Nausea (PT-141) — can be significant the first few doses
    • Flushing, BP changes
    • Increased mole darkening or new freckles (melanotan II)

Brand names & aliases

PT-141 is also sold or referenced as Bremelanotide®, Vyleesi®. These are registered trademarks of their respective owners and are listed for clinical clarity only — Peptide Calculator Log is not affiliated with, endorsed by, or sponsored by these companies.

PT-141 FAQ

Answers, not hype.

  • PT-141 (also marketed as Bremelanotide®, Vyleesi®) is a peptide in the Sexual category. It is a research peptide and is not FDA-approved for human use. The dose ranges shown (1–2 mg) are summarized from peer-reviewed research literature where evidence is preliminary.

  • PT-141 most commonly ships in 10 mg vials. Typical reconstitution volumes are 1, 2 ml of bacteriostatic water — choose the volume to land on a syringe-friendly unit count for your target dose.

  • Use the formula concentration = vial mg ÷ BAC water ml, then volume = dose mg ÷ concentration, then units = volume × 100 (for U-100). For example, a 10 mg vial reconstituted with 1 ml gives 10.00 mg/ml — at the typical low dose of 1 mg that resolves to 10.0 units. The free reconstitution calculator on this site verifies the math against your specific vial.

  • No. PT-141 is a research peptide and is not FDA-approved for human use in the United States as of April 2026. Any use must come through a licensed healthcare provider, typically via a compounding pharmacy.

  • Side-effect profiles for research peptides are characterized in published research rather than an FDA label. Most users report mild local reactions at the injection site, occasional fatigue, and headache in the first few doses. Long-term human safety data is limited for most research compounds. Discuss with your prescribing provider before starting.

  • No. The values shown are reference numbers summarized from authoritative sources — FDA-approved labels for approved compounds and peer-reviewed research for the rest. They are not personalized recommendations. Always follow your prescribing provider's instructions and verify every calculation against your vial label.

References & sources

Research peptide

PT-141 is a research peptide. It is not FDA-approved for human use. The ranges shown above are summarized from peer-reviewed clinical and pre-clinical literature, where evidence remains preliminary. Discuss any use with a licensed healthcare provider.

See the resources page for the full list of databases this site cross-checks against.

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