MOTS-c dosing reference
Common vial sizes, typical dose ranges, and a free reconstitution calculator pre-configured for MOTS-c. Not medical advice. Always verify against your vial label and your provider's protocol.
MOTS-c reconstitution
Pre-loaded with common MOTS-c values — adjust to your vial.
Inputs
MOTS-c common vial sizes: 5 mg, 10 mg. Typical dose range: 5–10 mg. Research publications. Not medical advice.
- That dose needs 200.0 units — more than fits in one U-100 syringe (100). Consider a higher concentration or split the dose.
for a 5 mg dose
- Concentration
- 2.50 mg/ml
- Volume
- 2.000 ml
- Per ml
- 100 u
Not medical advice. Always verify against your vial label and your provider's instructions. Re-check before drawing.
About MOTS-c
Metabolic peptides target mitochondrial regulation (MOTS-c), fat metabolism (AOD-9604, 5-Amino-1MQ), and metabolic flexibility.
How it's used
Subcutaneous injection, frequency varies — MOTS-c is typically weekly, AOD-9604 daily fasted.
Storage
Refrigerate reconstituted vials.
Watch for
- Hunger fluctuations
- Sleep changes in some users
- Limited rigorous human data for most compounds
Protocols using MOTS-c
MOTS-c vs other Metabolic peptides
3 compounds comparedReference dose ranges for the metabolic category. Tap any compound to open its full reference page.
| Compound | Brand names | Typical dose | Vial sizes | Status |
|---|---|---|---|---|
| MOTS-c | — | 5–10 mg | 5, 10 mg | Research |
| AOD-9604 | — | 0.25–0.5 mg | 2, 5 mg | Research |
| 5-Amino-1MQ | — | 50–150 mg | 50, 100 mg | Research |
Dose ranges summarized from FDA-approved labels (for approved compounds) and peer-reviewed research (for the rest). See the resources page for source databases.
MOTS-c FAQ
Answers, not hype.
MOTS-c is a peptide in the Metabolic category. It is a research peptide and is not FDA-approved for human use. The dose ranges shown (5–10 mg) are summarized from peer-reviewed research literature where evidence is preliminary.
MOTS-c most commonly ships in 5, 10 mg vials. Typical reconstitution volumes are 2, 3 ml of bacteriostatic water — choose the volume to land on a syringe-friendly unit count for your target dose.
Use the formula concentration = vial mg ÷ BAC water ml, then volume = dose mg ÷ concentration, then units = volume × 100 (for U-100). For example, a 5 mg vial reconstituted with 2 ml gives 2.50 mg/ml — at the typical low dose of 5 mg that resolves to 200.0 units. The free reconstitution calculator on this site verifies the math against your specific vial.
No. MOTS-c is a research peptide and is not FDA-approved for human use in the United States as of April 2026. Any use must come through a licensed healthcare provider, typically via a compounding pharmacy.
Side-effect profiles for research peptides are characterized in published research rather than an FDA label. Most users report mild local reactions at the injection site, occasional fatigue, and headache in the first few doses. Long-term human safety data is limited for most research compounds. Discuss with your prescribing provider before starting.
No. The values shown are reference numbers summarized from authoritative sources — FDA-approved labels for approved compounds and peer-reviewed research for the rest. They are not personalized recommendations. Always follow your prescribing provider's instructions and verify every calculation against your vial label.
Other Metabolic peptides
References & sources
Research peptideMOTS-c is a research peptide. It is not FDA-approved for human use. The ranges shown above are summarized from peer-reviewed clinical and pre-clinical literature, where evidence remains preliminary. Discuss any use with a licensed healthcare provider.
- PubMed research literaturePeer-reviewed research on MOTS-c. Evidence is preliminary; MOTS-c is not FDA-approved for human use.
- ClinicalTrials.govNIH database of registered clinical trials involving MOTS-c, completed or in progress.
See the resources page for the full list of databases this site cross-checks against.
Track MOTS-c in the app
History, reminders, body-map injection rotation, Apple Watch logging, and a doctor-ready PDF — all bundled with the calculator.
Download on theApp Store