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GLP-116+ weeks3 phases

Semaglutide — Gentle Start

Slower ramp for sensitive users — 8 weeks at each dose

Dose ladder

  2. Phase 1 / 3
    Intro
    Weeks 1–8
    0.25 mg
  4. Phase 2 / 3
    Build
    Weeks 9–16
    0.5 mg
  6. Phase 3 / 3
    Hold
    Week 17+
    1 mg

What you'll need

Reference defaults for Semaglutide — Gentle Start. Your provider may set different values — adjust as needed.

  • Vial
    10 mg
    starting size
  • BAC water
    2 ml
    for reconstitution
  • Concentration
    5.00 mg/ml
    computed
  • Duration
    16+ weeks
    3 phases

How the app runs this for you

  • Auto-advance phases

    Semaglutide — Gentle Start ramps automatically week by week — no manual tracking. The current phase and remaining weeks are visible on the home tab and the lock-screen widget.

  • Smart reminders

    Per-protocol notifications fire at your chosen time. Missed-dose detection flags any log >15 minutes late, with one-tap resolve from the lock screen.

  • Body-map rotation

    Each log records the injection site. The body map remembers recency so you don't reuse the same spot — especially important on multi-week protocols.

Side effects to watch for

Common in the GLP-1 category. The iOS app lets you track all of these on a timeline and surfaces patterns as your body adapts.

  • Nausea, vomiting, diarrhea, constipation — most pronounced in the first weeks of titration
  • Reduced appetite (the intended effect, but watch for muscle loss without protein intake)
  • Fatigue, headache, dizziness early in titration
  • Rare but serious: pancreatitis, gallbladder issues, severe dehydration

Defaults

Vial size
10 mg
BAC water
2 ml
Concentration
5.00 mg/ml
Total weeks
16+

Uses Semaglutide. Typical dose range: 0.25–2.4 mg. Public clinical dosing guidance. Not medical advice.

How Semaglutide — Gentle Start compares to other GLP-1 protocols

5 protocols compared

Quick read of the dose ladders, durations, and concentrations across the glp-1 category.

ProtocolPeptideDurationPhasesConcentration
Semaglutide — Gentle Startsemaglutide16+ weeks35.00 mg/ml
10 mg / 2 ml
Semaglutide — Standard TitrationPopularsemaglutide16+ weeks55.00 mg/ml
10 mg / 2 ml
Tirzepatide — Standard TitrationPopulartirzepatide20+ weeks615.00 mg/ml
30 mg / 2 ml
Tirzepatide — Aggressivetirzepatide12+ weeks615.00 mg/ml
30 mg / 2 ml
Retatrutide — Escalatingretatrutide16+ weeks410.00 mg/ml
20 mg / 2 ml

Semaglutide — Gentle Start FAQ

Answers, not hype.

  • Semaglutide — Gentle Start is a 16-week GLP-1 protocol using Semaglutide. Slower ramp for sensitive users — 8 weeks at each dose

  • The standard cycle is 16+ weeks across 3 dose phases. Phase 1 (Intro) starts at 0.25 mg per dose; the final phase (Hold) reaches 1 mg. Individual response and provider guidance can extend or shorten the timeline.

  • Semaglutide — Gentle Start defaults to a 10 mg vial reconstituted with 2 ml of bacteriostatic water — a concentration of 5.00 mg/ml. The reconstitution calculator on this site lets you adjust to whatever vial size you actually have.

  • Semaglutide is FDA-approved, and protocols similar to Semaglutide — Gentle Start appear in the prescribing information. The specific schedule shown here is a starting template — your provider may adjust it based on individual response and tolerability.

  • Most GLP-1 protocols share a common side-effect pattern documented on the parent peptide page. Track them in a timeline view (the iOS app does this automatically) so you can see whether symptoms are settling at the current dose or worsening — that is the signal that determines whether to advance the next phase or hold.

  • No. Semaglutide — Gentle Start is a reference template summarizing patterns from authoritative sources. It is not a personalized treatment plan. Talk to a licensed healthcare provider before starting, modifying, or stopping any peptide protocol.

More GLP-1 protocols

Run this protocol on autopilot

The iOS app advances this ramp week by week, fires reminders, and keeps a doctor-ready record.

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